Antithrombin activity and disaccharide composition of dermatan sulfate from different bovine tissues

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Isolation of dermatan sulfate proteoglycans from mature bovine articular cartilages.

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Fibrinogen Inhibits the Heparin Cofactor 11-Mediated Antithrombin Activity of Dermatan Sulfate

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Fibrinogen Inhibits the Heparin Cofactor 11-Mediated Antithrombin Activity of Dermatan Sulfate

Dermatan sulfate is a naturally occurring antithrombotic glycosaminoglycan. The antithrombin activity of several dermatan sulfate preparations has been measured in whole human plasma and found to be -55% of that in purified systems. Kinetic studies under pseudo-first-order conditions indicated that the reduction in antithrombin activity of dermatan sulfate in plasma compared with that in buffer...

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ژورنال

عنوان ژورنال: Glycobiology

سال: 2007

ISSN: 0959-6658,1460-2423

DOI: 10.1093/glycob/cwm136